A changing chapter.
An informed choice.
THE SOURCE NOTES
Provider pages describe offers. Studies address specific questions. Regulatory and dermatology sources add a different kind of context. Each record shows when we last retrieved that source.
Provider offer
Current estriol 0.3%, vitamin C 5%, hydrolyzed hyaluronic acid 0.5% formula, $48/month starting offer, precautions and manufacturer claims; dedicated visit CTA app.coreagerx.com/go/timeout verified from the product page. No personalized checkout or exact-product randomized trial verified.
Source checked: 2026-09-27
Provider offer
Advertised $150 three-month supply and prescription pathway. Marketing percentages need the underlying study context.
Source checked: 2026-09-24
Provider-hosted study report
A 12-week, single-site, randomized, double-blind, vehicle-controlled study of 90 women across three groups. Not a head-to-head trial of current retail brands.
Source checked: 2026-09-24
Provider offer
Advertised monthly equivalent with a two-month supply, prescription access, and explicitly self-reported patient outcome claims.
Source checked: 2026-09-24
Provider offer
Advertised $149 for a 90-day supply (90 mL). Exact dispensed formulation and eligibility require confirmation.
Source checked: 2026-09-24
Provider process
Public intake, clinician decision, and ordering process; advertised timing is not a service guarantee.
Source checked: 2026-09-24
Regulatory guidance
Compounded drugs are not FDA-approved; FDA does not review them for safety, effectiveness, or quality before marketing.
Source checked: 2026-09-27
Regulatory guidance
No FDA-approved drugs contain estriol. FDA does not establish estriol as a safer form of estrogen. General hormone-therapy guidance is not a product-specific facial risk estimate.
Source checked: 2026-09-27
Dermatology guidance
Practical advice on dryness, sun protection, changing skin, and when an examination is needed.
Source checked: 2026-09-27
Published study abstract
Compared estriol and estradiol preparations in 59 women over six months. Historical formulations and limited follow-up do not establish current-brand equivalence or long-term safety.
Source checked: 2026-09-26
Published study abstract
Small pilot: 8 estriol and 10 estradiol participants. Useful as early research, not a reliable probability of benefit.
Source checked: 2026-09-24
Published study abstract
A small, short study cannot exclude uncommon or delayed effects, or establish no absorption for every formulation.
Source checked: 2026-09-24
Regulatory consumer guidance
Online pharmacy warning signs, licensing checks, prescription requirements, and pharmacist access. This journal has not inspected or independently certified a dispensing pharmacy.
Source checked: 2026-09-27
Dermatology guidance
Assessment and individualized treatment of persistent dry skin. General care guidance does not establish the suitability of estriol.
Source checked: 2026-09-26
Dermatology guidance
Retinoid terminology, irritation, suitability, and sun protection. Not a trial of estriol and retinoid combinations.
Source checked: 2026-09-26
Dermatology guidance
Potential irritation when exfoliation is added to retinoids and other actives; does not provide an estriol prescription schedule.
Source checked: 2026-09-26
Dermatology guidance
Sun and visible-light protection, gentle skincare, and professional care for diagnosed melasma. Not evidence that facial estriol treats melasma.
Source checked: 2026-09-26
Dermatology guidance
General expectations, moisturizer effects, product burden, and sun protection. Timelines are not specific to a compounded estriol product.
Source checked: 2026-09-26
Dermatology guidance
Realistic expectations and focused skincare choices; does not establish comparative efficacy of the brands in this journal.
Source checked: 2026-09-26
Provider formula page
Estriol 0.3%, DMAE 3%, hyaluronic acid 0.5% listing. Categorical no-systemic-effect and broad clinically-proven claims are not adopted. Current price, full base and fulfillment unverified.
Source checked: 2026-09-27
Dermatology guidance
Broad-spectrum SPF, water resistance, reapplication and sensitive-skin information; not a compatibility trial with compounded estriol.
Source checked: 2026-09-27
Regulatory consumer guidance
General storage and expiration guidance; does not establish a temperature, travel allowance or color threshold for a particular compounded preparation.
Source checked: 2026-09-27
Professional society guidance
General causes and assessment of persistent itch; not an estriol efficacy study.
Source checked: 2026-09-27
Professional society guidance
General cleansing technique; does not establish a particular cleanser or hormone regimen.
Source checked: 2026-09-27
Professional society guidance
Cosmetic product testing and fragrance-label distinctions. Not a hormone eligibility or systemic-safety test.
Source checked: 2026-09-27
Provider offer
Final sales destination of /go/timeout: twelve months $576 ($48/month), six months $330, three months $189 and one month $75. Some monthly display rates differ slightly from the total divided by its period. No auto-billing and non-approval refund advertised; no checkout or fulfillment verified.
Source checked: 2026-09-27
Provider offer
Official product ingredients, displayed prices and subscription renewal, checked October 4, 2026. No patient care or fulfillment test performed.
Source checked: 2026-09-27
Provider shipping reference and supplied service information
Homepage shipping reference; customer service and payment details supplied for this review, without a checkout or timed support test
Source checked: 2026-10-12
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Clinical background
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Regulatory guidance
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Official product or purchase terms
Public source checked for this editorial review; no product-use or transaction test.
Source checked: 2026-10-14
Research
Original 2026 conference abstract P-124 and its complete table, PDF page50; text and rendered page reviewed
Source checked: 2026-10-21
Research
Primary full article: methods, main results, participant table, figure captions, discussion and funding reviewed on publisher site
Source checked: 2026-10-21
Regulatory guidance
Official FDA questions-and-answers page read directly; concise editorial summary retained
Source checked: 2026-10-21